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Translocation

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Updated October 24, 2007

Definition:

A type of chromosomal abnormality in which a piece of a chromosome has broken off and attached to another chromosome.

Multiple types of translocations may occur, but balanced translocations are present in one or both partners in roughly 5% of couples who experience recurrent miscarriages. A person with a balanced translocation will have all the necessary genetic material for normal life and will usually have no symptoms from the translocation. However, that person will have a 50% chance of producing offspring with an unbalanced translocation. Pregnancies involving an unbalanced translocation have greater odds of miscarriage due to missing or extra genetic material in the developing baby.

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  5. Translocation Definition - Chromosomal Translocation - Balanced Translocation

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